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Meta-analysis is a method of synthesis of quantitative data from multiple independent studies addressing a common research question. An important part of this method involves computing a combined effect size across all of the studies.
Meta-analysis is the preferred technique of quantitative research synthesis in many fields, such as medical science.It is a statistical technique that combines measures of effect size from a number of studies to calculate an overall measure.
A systematic review is a scholarly synthesis of the evidence on a clearly presented topic using critical methods to identify, define and assess research on the topic. [1] A systematic review extracts and interprets data from published studies on the topic (in the scientific literature), then analyzes, describes, critically appraises and summarizes interpretations into a refined evidence-based ...
The aim of the PRISMA statement is to help authors improve the reporting of systematic reviews and meta-analyses. [3] PRISMA has mainly focused on systematic reviews and meta-analysis of randomized trials, but it can also be used as a basis for reporting reviews of other types of research (e.g., diagnostic studies, observational studies).
Meta-analysis is a method used to combine the results of different trials in order to obtain a quantitative synthesis. The size of individual clinical trials is often too small to detect treatment effects reliably. Meta-analysis increases the power of statistical analyses by pooling the results of all available trials.
The principal methodology in health secondary research is the systematic review, commonly using meta-analytic statistical techniques. Other methods of synthesis, like realist reviews and meta-narrative reviews, have been developed in the 21st century. [5]
Systematic reviews may include meta-analysis results. [6] The first edition of the Handbook of Research Synthesis aided the development of various analysis techniques that could be used in systematic review articles, thereby developing this form of literature. [6] Exemplar of Alzheimer's Disease review article
A meta-regression can be classified in the same way—meta-regression and network meta-regression—depending on the number of distinct treatments in the regression analysis. Meta-analysis (and meta-regression) is often placed at the top of the evidence hierarchy provided that the analysis consists of individual participant data of randomized ...