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Silicone sheets and gels Dr. Turegano says silicone sheets and gels, which you can buy at your pharmacy and certain retail outlets, can reduce the size, color, and texture of keloids.
The exact mechanism of action of silicone gel sheeting has not been fully studied. Currently, many proposed mechanisms explain the efficacy of such treatment, including the occlusion and hydration effect, increased body surface temperature, polarized electric charge, immunological effects, etc. [9] The occlusion and hydration effect is the most studied mechanism of action.
A hypertrophic scar is a cutaneous condition characterized by deposits of excessive amounts of collagen which gives rise to a raised scar, but not to the degree observed with keloids. [1] Like keloids, they form most often at the sites of pimples, body piercings, cuts and burns. They often contain nerves and blood vessels.
Surgical excision of hypertrophic or keloid scars is often associated to other methods, such as pressotherapy or silicone gel sheeting. Lone excision of keloid scars, however, shows a recurrence rate close to 45%.
A keloid scar is benign and not contagious, but sometimes accompanied by severe itchiness, pain, [2] and changes in texture. In severe cases, it can affect movement of skin. In the United States, keloid scars are seen 15 times more frequently in people of sub-Saharan African descent than in people of European descent. [3]
To treat hypertrophic scars (raised, tense, stiff and itchy scars) and limit their effect on physical function and everyday activities, silicone sheeting and compression garments are recommended. [ 98 ] [ 99 ] [ 100 ] In the developing world, significant burns may result in social isolation, extreme poverty and child abandonment .