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In the ‘80s, researchers set out to test a medication called sildenafil citrate for treating high blood pressure and angina ... (a condition called pulmonary arterial hypertension, or PAH)
Generic sildenafil (and brand-name Viagra) is a medication for the treatment of ED, Raynaud’s phenomenon, and pulmonary arterial hypertension. To understand how Viagra works, we need to look at ...
It also concluded that sildenafil is generally safe for younger and older men with and without hypertension. ... this version of sildenafil is FDA approved to treat pulmonary arterial hypertension ...
Sildenafil, sold under the brand name Viagra among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. [4] [8] It is also sometimes used off-label for the treatment of certain symptoms in secondary Raynaud's phenomenon. [9]
Sildenafil was the first effective oral treatment available for ED. Because PDE5 is also present in the smooth muscle of the walls of the arterioles within the lungs, two PDE5 inhibitors, sildenafil and tadalafil, are FDA-approved for the treatment of pulmonary hypertension.
Pulmonary hypertension (PH or PHTN) is a condition of increased blood pressure in the arteries of the lungs. [7] Symptoms include shortness of breath, fainting, tiredness, chest pain, swelling of the legs, and a fast heartbeat. [7] [1] The condition may make it difficult to exercise. [7] Onset is typically gradual. [8]