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Poorly cohesive gastric carcioma (signet-ring cell type) x400, H&E stain . Poorly cohesive gastric carcinoma (dyscohesive carcinoma, carcinoma with a lack of intercellular connections) is a malignant tumour of epithelial origin, characterized by diffuse distribution of tumour cells, isolated from each other or in small groups.
In histology, a signet ring cell is a cell with a large vacuole. The malignant type is seen predominantly in carcinomas . Signet ring cells are most frequently associated with stomach cancer , [ 1 ] but can arise from any number of tissues including the prostate , [ 2 ] bladder , gallbladder , [ 3 ] breast , colon , [ 4 ] ovarian stroma and ...
A signet ring cell carcinoma of the stomach. Signet ring cells are seen in the lower half of the image. Gastric epithelium is seen in the upper half of the image. H&E stain. SRCCs are named due to their resemblance to signet rings, which result from the formation of large vacuoles full of mucin that displaces the nucleus to the cell's periphery ...
Pseudomyxoma peritonei (PMP) is a clinical condition caused by cancerous cells (mucinous adenocarcinoma) that produce abundant mucin or gelatinous ascites. [1] The tumors cause fibrosis of tissues and impede digestion or organ function, and if left untreated, the tumors and mucin they produce will fill the abdominal cavity.
About 70% occur in the stomach, 20% in the small intestine and less than 10% in the esophagus. Small tumors are generally not aggressive, especially when cell division rate is slow. GIST tumors commonly metastasize to the liver (in 28% of cases) and/or to the greater omentum, lesser omentum, or mesentery (in 30% of cases). Less common areas of ...
The narrowing is caused by a ring of mucosal tissue (which lines the esophagus) or muscular tissue. [1] A Schatzki ring is a specific type of "esophageal ring", and Schatzki rings are further subdivided into those above the esophagus/stomach junction (A rings), [2] and those found at the squamocolumnar junction in the lower esophagus (B rings ...
Cyclic vomiting syndrome (CVS) is a chronic functional condition of unknown pathogenesis.CVS is characterized as recurring episodes lasting a single day to multiple weeks. Each episode is divided into four phases: inter-episodic, prodrome, vomiting, and recove
Krukenberg tumors often come to the attention when they cause abdominal or pelvic pain, bloating, ascites, or pain during sexual intercourse.Krukenberg tumors can occasionally provoke a reaction of the ovarian stroma which leads to hormone production, that results in vaginal bleeding, a change in menstrual habits, or hirsutism, [3] or occasionally virilization [4] as a main symptom.