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Patients present with an acute onset of swelling, pain, erythema, prominent tenderness, warmness and limited range of motion in both ankles. [1] [2] Lower legs and heels may also be involved, however the distal parts of feet and toes are usually spared. Patients may also experience high-graded fever, pitting edema and hypotension.
Lymphedema is most frequently a complication of cancer treatment or parasitic infections, but it can also be seen in a number of genetic disorders. Tissues with lymphedema are at high risk of infection because the lymphatic system has been compromised. [3] Though incurable and progressive, a number of treatments may improve symptoms. [2]
Women of any weight may be affected [2] [3] and the fat is resistant to traditional weight-loss methods. [4] There is no cure and typically it gets worse over time, pain may be present, and people bruise more easily. [2] Over time mobility may be reduced, and due to reduced quality of life, people often experience depression. [3]
It could be that "people get on GLP-1s to lose weight, and as a consequence of the weight loss, feel better.” But it’s also possible that GLP-1s are benefiting the body in other ways, he says.
The condition is commonly associated with vascular and cardiac changes associated with aging but can be caused by many other conditions, including congestive heart failure, kidney failure, liver cirrhosis, portal hypertension, trauma, alcoholism, altitude sickness, pregnancy, hypertension, sickle cell anemia, a compromised lymphatic system or merely long periods of time sitting or standing ...
Per the Mayo Clinic, Lymphedema results from “a blockage in your lymphatic system, which is part of your immune system. The blockage prevents lymph fluid from draining well, and the fluid ...
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