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  2. Warfarin - Wikipedia

    en.wikipedia.org/wiki/Warfarin

    Warfarin should not be given to people with heparin-induced thrombocytopenia until platelet count has improved or normalised. [39] Warfarin is usually best avoided in people with protein C or protein S deficiency, as these thrombophilic conditions increase the risk of skin necrosis, which is a rare but serious side effect associated with ...

  3. List of drugs by year of discovery - Wikipedia

    en.wikipedia.org/wiki/List_of_drugs_by_year_of...

    Governmental approval Patented expired Synthesis discoverer ... the first man-made antibiotic. In 1927 Erik Rotheim patented the first aerosol spray can ...

  4. Anticoagulant - Wikipedia

    en.wikipedia.org/wiki/Anticoagulant

    Idarucizumab is a monoclonal antibody, approved by the US FDA in 2015, that reverses the effect of dabigatran by binding to both free and thrombin-bound dabigatran. [ 116 ] [ 117 ] Andexanet alfa is a recombinant modified human factor Xa decoy that reverses the effect of factor Xa inhibitors by binding at the active sites of factor Xa inhibitor ...

  5. U.S. FDA Approves ELIQUIS® (apixaban) to Reduce the ... - AOL

    www.aol.com/news/2013-01-02-us-fda-approves...

    U.S. FDA Approves ELIQUIS ® (apixaban) to Reduce the Risk of Stroke and Systemic Embolism in Patients with Nonvalvular Atrial Fibrillation ELIQUIS Demonstrated Superior Risk Reductions Versus ...

  6. J&J Wins Blockbuster Approval to Market Xarelto for Stroke ...

    www.aol.com/news/2011-11-05-jj-wins-blockbuster...

    The FDA has given Johnson & Johnson (NYS: JNJ) the green light to market Xarelto to prevent stroke among patients suffering from atrial fibrillation -- opening up a blockbuster market involving ...

  7. List of withdrawn drugs - Wikipedia

    en.wikipedia.org/wiki/List_of_withdrawn_drugs

    Cardiac valvular disease, pulmonary hypertension, cardiac fibrosis; [3] [23] re-approved in June 2020 for the treatment of seizures associated with Dravet syndrome, under FDA orphan drug rules. Fenoterol: 1990 New Zealand Asthma mortality. [3] Feprazone: 1984 Germany, UK Cutaneous reaction, multiorgan toxicity. [3] Fipexide: 1991 France ...

  8. A 75-year-old woman was killed in 1995. A man is now charged ...

    www.aol.com/75-old-woman-killed-1995-161646107.html

    Willie Rodgers lived in the same neighborhood as the victim, 75-year-old Earnestine Mortimore, police said.

  9. History of the Food and Drug Administration - Wikipedia

    en.wikipedia.org/wiki/History_of_the_Food_and...

    The FDA began enforcing its new powers against drug manufacturers who could not substantiate the efficacy claims made for their drugs, and the United States Court of Appeals for the Ninth Circuit ruling in Alberty Food Products Co. v. United States (1950) found that drug manufacturers could not evade the "false therapeutic claims" provision of ...