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In 2022, the combination azelastine/fluticasone was the 299th most commonly prescribed medication in the United States, with more than 300,000 prescriptions. [ 8 ] [ 9 ] References
Treatment can be given as an injection, tablet, sprays or sublingual drops. The gradual increase of allergen causes the immune system to become less sensitive to the substance ( desensitization ), reducing symptoms during future exposures to the allergen, and possibly preventing new allergies.
Azelastine, sold under the brand name Astelin among others, is a H 1 receptor-blocking medication primarily used as a nasal spray to treat allergic rhinitis (hay fever) and as eye drops for allergic conjunctivitis. [5] [6] Other uses may include asthma and skin rashes for which it is taken by mouth. [7]
A decongestant, or nasal decongestant, is a type of pharmaceutical drug that is used to relieve nasal congestion in the upper respiratory tract.The active ingredient in most decongestants is either pseudoephedrine or phenylephrine (the latter of which has disputed effectiveness).
Unlike fluticasone furoate, which is approved in children as young as two years of age when used for allergies, fluticasone propionate is only approved for children four years and older. [12] [13] Fluticasone propionate was patented in 1980, and approved for medical use in 1990. [14] It is available as a generic medication. [10]
Fluticasone Furoate is a corticosteroid medication primarily used to treat allergic rhinitis (hay fever) and non-allergic (perennial) rhinitis. It is also indicated for the treatment of nasal polyps in adults. Additionally, fluticasone furoate nasal spray may be prescribed for the management of symptoms associated with sinusitis.