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Keratin 1 is a Type II intermediate filament (IFs) of the intracytoplasmatic cytoskeleton. Is co-expressed with and binds to Keratin 10, a Type I keratin, to form a coiled coil heterotypic keratin chain. Keratin 1 and Keratin 10 are specifically expressed in the spinous and granular layers of the epidermis. [5]
Keratin (/ ˈ k ɛr ə t ɪ n / [1] [2]) is one of a family of structural fibrous proteins also known as scleroproteins. It is the key structural material making up scales , hair , nails , feathers , horns , claws , hooves , and the outer layer of skin in vertebrates.
3881 16671 Ensembl ENSG00000094796 ENSG00000262993 ENSMUSG00000057723 UniProt Q15323 Q61897 RefSeq (mRNA) NM_002277 NM_013570 RefSeq (protein) NP_002268 NP_038598 Location (UCSC) Chr 17: 41.39 – 41.4 Mb Chr 11: 99.91 – 99.92 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Keratin, type I cuticular Ha1 is a protein that in humans is encoded by the KRT31 gene. Function The protein ...
Keratin, type II cuticular Hb1 is a protein that in humans is encoded by the KRT81 gene. [5] [6] [7]The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails.
[1] [2] These two groups of keratins were named as type I and type II keratins. [2] These two categories also represent the first two categories of the superfamily of intermediate filament proteins. Keratins in this table are classified in the first two columns according to the nomenclature established in 2006. [3]
Keratins belong to two types - acidic Type I and neutral-basic Type II, further categorized into Type I a and b, and Type II a and b. The initial step in forming keratin is the alignment of type I and type II keratin polypeptides to create a heterodimer, which then aggregates into higher-order structural units. [2]
56735 Ensembl ENSG00000139648 ENSMUSG00000051879 UniProt Q3SY84 Q9R0H5 RefSeq (mRNA) NM_033448 NM_019956 RefSeq (protein) NP_258259 NP_064340 Location (UCSC) Chr 12: 52.54 – 52.55 Mb Chr 15: 101.64 – 101.65 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse KRT71 is a keratin gene. Keratins are intermediate filament proteins responsible for the structural integrity of epithelial ...
n/a Ensembl ENSG00000186442 n/a UniProt P12035 n/a RefSeq (mRNA) NM_057088 n/a RefSeq (protein) NP_476429 n/a Location (UCSC) Chr 12: 52.79 – 52.8 Mb n/a PubMed search n/a Wikidata View/Edit Human Keratin 3 also known as cytokeratin 3 is a protein that in humans is encoded by the KRT3 gene. Keratin 3 is a type II cytokeratin. It is specifically found in the corneal epithelium together with ...