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Metanephric adenoma (MA) is a rare, benign tumour of the kidney, that can have a microscopic appearance similar to a nephroblastoma (Wilms tumours), [1] or a papillary renal cell carcinoma. It should not be confused with the pathologically unrelated, yet similar sounding, mesonephric adenoma .
Nephrogenic adenoma is a benign growth typically found in the urinary bladder. It is thought to result from displacement and implantation of renal tubular cells, as this entity in kidney transplant recipients has been shown to be kidney donor derived. [1] This entity should not be confused with the similar-sounding metanephric adenoma.
Histopathologic types of kidney tumor, with relative incidences and prognoses. Cystic nephroma is seen at bottom right in pie chart. cystic partially differentiated nephroblastoma; cystic standard nephroblastoma (cystic Wilm's tumor) cystic mesoblastic nephroma; cystic renal cell carcinoma; other renal cysts
Wilms' tumor is a malignant tumor containing metanephric blastema, stromal and epithelial derivatives. Characteristic is the presence of abortive tubules and glomeruli surrounded by a spindled cell stroma. The stroma may include striated muscle, cartilage, bone, fat tissue, and fibrous tissue. Dysfunction is caused when the tumor compresses the ...
Immunohistochemistry staining of tumor samples show that it is indeed positive for mesothelial-markers (calretinin, WT1, and CK6). [3] It is the most common extratesticular neoplasm after lipoma, and accounts for 30% of these masses. [4] On the other hand, adenomatoid tumors are the most common tumors of testicular adnexa.
Metanephric dysplastic hematoma of the sacral region (MDHSR) has been described by Cozzutto and Lazzaroni-Fossati in 1980, [1] by Posalaki et al. in 1981 [2] and by Cozzutto et al. in 1982. [3] Three additional cases were seen by Finegold.
The TNM Classification of Malignant Tumors (TNM) is a globally recognised standard for classifying the anatomical extent of the spread of malignant tumours (cancer). It has gained wide international acceptance for many solid tumor cancers, but is not applicable to leukaemia or tumors of the central nervous system .
The WHO/ISUP system is histological tumor grading system for renal cell carcinoma, suggested by the International Society of Urologic Pathologists (ISUP) in 2012 to diagnose tumor grades based on nucleolar prominence. [34] Currently recommended by the WHO, this four-tiered WHO/ISUP grading system has also been validated for PRCC. [34]