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Baclofen, sold under the brand name Lioresal among others, is a medication used to treat muscle spasticity, such as from a spinal cord injury or multiple sclerosis. [ 8 ] [ 9 ] It may also be used for hiccups and muscle spasms near the end of life, [ 9 ] and off-label to treat alcohol use disorder [ 10 ] [ 11 ] or opioid withdrawal symptoms. [ 12 ]
Suvorexant is used for the treatment of insomnia, characterized by difficulties with sleep onset and/or sleep maintenance, in adults. [2] [6] At a dose of 15 to 20 mg and in terms of treatment–placebo difference, it reduces time to sleep onset by up to 10 minutes, reduces time awake after sleep onset by about 15 to 30 minutes, and increases total sleep time by about 10 to 20 minutes. [2]
A baclofen pump has been used to treat patients of all ages exhibiting muscle spasticity along with dystonia. The pump delivers baclofen via a catheter to the thecal space surrounding the spinal cord. The pump itself is placed in the abdomen. It can be refilled periodically by access through the skin. Baclofen can also be taken in tablet form [40]
Salk Institute researchers have identified a key protein that may help users of GLP-1 drugs such as Ozempic and Wegovy maintain muscle mass while losing weight.
There is evidence, albeit limited, of the clinical effectiveness of THC and CBD extracts, [126] baclofen, [127] dantrolene, [128] diazepam, [129] and tizanidine. [130] [131] [132] In the most complicated cases intrathecal injections of baclofen can be used. [133] There are also palliative measures like castings, splints or customized seatings. [31]
The best time to take metformin depends on the medication type and dosage. Some people take metformin once, twice or even three times a day, depending on the type of metformin (tablet or liquid ...
On Saturday, Jan. 25, legendary director Steven Spielberg and star Drew Barrymore opened up about their work on E.T. the Extra-Terrestrial and how Barrymore, who was just 6 at the time, shaped her ...
Baclofen, diazepam and dantrolene remain the three most commonly used pharmacologic agents in the treatment of spastic hypertonia. Baclofen is generally the drug of choice for spinal cord types of spasticity, while sodium dantrolene is the only agent which acts directly on muscle tissue. Tizanidine is also available.