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In premenopausal women, 40 to 75% of circulating testosterone is derived from peripheral metabolism of DHEA-S, and in postmenopausal women, over 90% of estrogens, mainly estrone, are derived from peripheral metabolism of DHEA-S. [2] A study found that administration of exogenous DHEA-S in women who were pregnant increased circulating levels of ...
Plasma levels of DHEA in adult men are 10 to 25 nM, in premenopausal women are 5 to 30 nM, and in postmenopausal women are 2 to 20 nM. [25] Conversely, DHEA-S levels are an order of magnitude higher at 1–10 μM. [25] Levels of DHEA and DHEA-S decline to the lower nanomolar and micromolar ranges in men and women aged 60 to 80 years. [25]
Prasterone, also known as dehydroepiandrosterone (DHEA) and sold under the brand name Intrarosa among others, is a medication as well as over-the-counter dietary supplement which is used to correct DHEA deficiency due to adrenal insufficiency or old age, as a component of menopausal hormone therapy, to treat painful sexual intercourse due to vaginal atrophy, and to prepare the cervix for ...
DHEA levels are lower in those with depression, so supplementation may help. A 2005 placebo-controlled study looked at men and women aged 45 to 65 with midlife-onset major or minor depression.
It continues throughout puberty, with adrenal androgen levels progressively increasing until reaching maximal levels in young adulthood, around the age of 20 years. [1] [5] Circulating DHEA-S levels specifically peak in humans at about age 19 or 20 years in females and around age 20 to 24 years in males. [2]
Estrogen levels, such as those in hormonal birth control, especially in women who smoke Low levels of dehydroepiandrosterone (DHEAS), an adrenal hormone Experiencing the first period at 10 or ...
Regarding the relative contributions of ovaries and adrenal glands to female androgen levels, in a study with six menstruating women the following observations have been made: [8] Adrenal contribution to peripheral T, DHT, A, DHEA and DHEA-S is relatively constant throughout the menstrual cycle .
Some women are sensitive to certain personal care products, such as scented vulvar washes and soaps, and it can cause an inflammatory reaction that may feel like burning or stinging pain, Dr ...