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Common side effects of fludrocortisone include high blood pressure, swelling, heart failure, and low blood potassium. [3] Other serious side effects can include low immune-system function, cataracts, muscle weakness, and mood changes. [3] Whether use of fludrocortisone during pregnancy is safe for the fetus is unknown. [5]
Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex of vertebrates, as well as the synthetic analogues of these hormones.Two main classes of corticosteroids, glucocorticoids and mineralocorticoids, are involved in a wide range of physiological processes, including stress response, immune response, and regulation of inflammation, carbohydrate metabolism ...
Hydrocortisone is the pharmaceutical term for cortisol used in oral administration, intravenous injection, or topical application.It is used as an immunosuppressive drug, given by injection in the treatment of severe allergic reactions such as anaphylaxis and angioedema, in place of prednisolone in patients needing steroid treatment but unable to take oral medication, and perioperatively in ...
Ocular effects: Topical steroid drops are frequently used after eye surgery but can also raise intraocular pressure (IOP) and increase the risk of glaucoma, cataract, retinopathy as well as systemic adverse effects. [14] Tachyphylaxis: The acute development of tolerance to the action of a drug after repeated doses. [15]
These preparations have the advantage of only affecting the targeted area, thereby reducing side effects or potential interactions. In this case, the main compounds used are beclometasone, budesonide, fluticasone, mometasone and ciclesonide. In rhinitis, sprays are used.
[10] [11] Side effects after long-term usage include eyesight damage, elevated blood sugar levels and adrenal gland disorders. [12] Topical hydrocortisone is available in several dosage forms such as solution, lotion, cream, ointment and spray. [19] Some brand names for topical hydrocortisone include Anusol HC, Cortizone 10, and Synacort. [19]
Hydrocortisone valerate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester. It can be used as a medicine to treat itching, swelling, and other ...
It is a synthetic hydrocortisone derivative. The fluorine substitution at position 9 in the steroid nucleus greatly enhances its activity. It was first synthesized in 1959 in the Research Department of Syntex Laboratories S.A. Mexico City. [3] Preparations containing it were first marketed under the brand name Synalar.