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Testosterone can be taken by a variety of different routes of administration. [2] [3] These include oral, buccal, sublingual, intranasal, transdermal (gels, creams, patches, solutions), vaginal (creams, gels, suppositories), rectal (suppositories), by intramuscular or subcutaneous injection (in oil solutions or aqueous suspensions), and as a subcutaneous implant.
Pharmacokinetics of testosterone esters Testosterone ester Form Route T max Tooltip Time to peak levels t 1/2 Tooltip Elimination half-life MRT Tooltip Mean residence time; Testosterone undecanoate: Oil-filled capsules: Oral? 1.6 hours: 3.7 hours Testosterone propionate: Oil solution: Intramuscular injection? 0.8 days: 1.5 days Testosterone ...
Testosterone is a medication and naturally occurring steroid hormone. [9] It is used to treat male hypogonadism, gender dysphoria, and certain types of breast cancer. [9] [10] It may also be used to increase athletic ability in the form of doping. [9] It is unclear if the use of testosterone for low levels due to aging is beneficial or harmful ...
Testosterone propionate was introduced in 1937 by Schering AG in Germany under the brand name Testoviron. [5] It was the first commercially available form of testosterone, and the first testosterone ester, to be introduced. [4] [20] The medication was the major form of testosterone used medically before 1960. [5]
Testosterone enanthate is used primarily in androgen replacement therapy. [4] [15] It is the most widely used form of testosterone in androgen replacement therapy. [4]The medication is specifically approved, in the United States, for the treatment of hypogonadism in men, delayed puberty in boys, and breast cancer in women. [16]
Testosterone undecanoate, an ester of testosterone and one of the most widely used androgen esters.. An androgen or anabolic steroid ester is an ester of an androgen/anabolic steroid (AAS) such as the natural testosterone or dihydrotestosterone (DHT) or the synthetic nandrolone (19-nortestosterone).
Sustanon is the preferred method of testosterone replacement in the United Kingdom as detailed in the British National Formulary. [ citation needed ] There was a brief shortage of Sustanon 250 during late 2011, due to shifting of manufacturing site, [ 7 ] and a further shortage in mid-2012 due to manufacturing problems.
With immunoassay-based techniques, testosterone levels in premenopausal women have been found to be about 40 ng/dL (1.4 nmol/L) and DHT levels about 10 ng/dL (0.34 nmol/L). [5] [74] With radioimmunoassays, the ranges for testosterone and DHT levels in women have been found to be 20 to 70 ng/dL and 5 to 30 ng/dL, respectively. [74]
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