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2. Naltrexone - Wikipedia

   en.wikipedia.org/wiki/Naltrexone

   The consequence of relapse when weighing the best course of treatment for opiate use disorder remains a concern. Methadone and buprenorphine administration maintain greater drug tolerance while naltrexone allows tolerance to fade, leading to higher instances of an overdose in people who relapse and thus higher mortality.

3. Opioid withdrawal - Wikipedia

   en.wikipedia.org/wiki/Opioid_withdrawal

   The treatment of withdrawal in people with opioid use disorder also relies on symptomatic management and tapering with medications that replace typical opioids, including buprenorphine and methadone. The principle of managing the syndrome is to allow the concentration of drugs in blood to fall to near zero and reverse physiological adaptation.

4. Lofexidine - Wikipedia

   en.wikipedia.org/wiki/Lofexidine

   Lofexidine, sold under the brand name Lucemyra among others, [1] is a medication historically used to treat high blood pressure; today, it is more commonly used to help with the physical symptoms of opioid withdrawal. [2] It is taken by mouth. [3] It is an α 2A-adrenergic receptor agonist. [3]

5. Ozempic May Help You Cut Back On Alcohol. Here's Why.

   www.aol.com/ozempic-may-help-cut-back-180600586.html

   Medicines used to treat opioid use disorder bind to opioid receptors and either block the effects of opioid drugs like heroin, or activate the receptors enough to quell withdrawal symptoms and ...

6. Methadone - Wikipedia

   en.wikipedia.org/wiki/Methadone

   Treatment of opioid-dependent persons with methadone follows one of two routes: maintenance or withdrawal management. [23] Methadone maintenance therapy (MMT) usually takes place in outpatient settings. It is usually prescribed as a single daily dose medication for those who wish to abstain from illicit opioid use. Treatment models for MMT differ.

7. Tramadol - Wikipedia

   en.wikipedia.org/wiki/Tramadol

   Tramadol, sold under the brand name Ultram among others, [1] is an opioid pain medication and a serotonin–norepinephrine reuptake inhibitor (SNRI) used to treat moderately severe pain. [ 12 ] [ 16 ] When taken by mouth in an immediate-release formulation, the onset of pain relief usually begins within an hour. [ 12 ]