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Now, a new study from researchers at the University of Michigan reports that an estimated 15.6 million U.S. adults — or 5% — have taken at least one herbal supplement in the last 30 days that ...
For the study, researchers from the University of Michigan analyzed data from six herbal supplements previously considered potentially hepatotoxic (toxic to the liver), including ashwagandha ...
Furthermore, the researchers estimated that 15.6 million U.S. adults have taken at least one herbal supplement in the last 30 days that might be hepatotoxic or damaging to their liver.
Beyond adverse effects from the herb itself, "adulteration, inappropriate formulation, or lack of understanding of plant and drug interactions have led to adverse reactions that are sometimes life threatening or lethal." [3] Most of the adverse effects stated in this list are associated with only a small percentage of cases; they should be ...
These observations led to the recognition of PAs as potent hepatotoxic and genotoxic compounds. [10] In response to growing concerns about PA exposure, regulatory agencies around the world began to establish guidelines and regulations to limit PA levels in food, herbal products, and animal feed. [11]
A hepatotoxin (Gr., hepato = liver) is a toxic chemical substance that damages the liver. It can be a side-effect , but hepatotoxins are also found naturally, such as microcystins and pyrrolizidine alkaloids , or in laboratory environments, such as carbon tetrachloride , or far more pervasively in the form of ethanol (drinking alcohol).