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The eclipse period is a variable period starting from HIV exposure in which no existing test can detect HIV. The median duration of the eclipse period in one study was 11.5 days. The window period is the time between HIV exposure and when an antibody or antigen test can detect HIV. The median window period for antibody/antigen testing is 18 days.
An HIV antibody test usually detects the HIV antibodies within two to eight weeks, but can have a valid negative result for a long as 2 to 6 months after initial infection. Viral load tests can also be used to diagnose HIV infection, especially in children under 18 months born to mothers with HIV, where the presence of maternal antibodies ...
This is a timeline of HIV/AIDS, including but not limited to cases before 1980. Pre-1980s See also: Timeline of early HIV/AIDS cases Researchers estimate that some time in the early 20th century, a form of Simian immunodeficiency virus found in chimpanzees (SIVcpz) first entered humans in Central Africa and began circulating in Léopoldville (modern-day Kinshasa) by the 1920s. This gave rise ...
Previous generation tests relied on detecting patient antibodies alone; it takes about 3–4 weeks for the earliest antibodies to be detected. The p24 protein can be detected in a patient's blood as early as 2 weeks after infection, further reducing the window period necessary to accurately detect the HIV status of the patient. [15]
The window period for HIV may be up to three months, depending on the test method and other factors. RNA based HIV tests has the lowest window period. Modern and accurate testing abilities can cut this period to 25 days, 16 days, or even as low as 12 days, again, depending on the type of test and the quality of its administration and interpretation.
However, if HIV infection is already present then PEP should not be started. HIV testing should be repeated four to six weeks and three months after exposure. [17] People may experience signs and symptoms of acute HIV infection, including fever, fatigue, myalgia, and skin rash, while taking PEP. CDC recommends seeking medical attention for ...
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