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Eucalyptol makes up about 70–90% of eucalyptus oil. [2] [3] Eucalyptol forms crystalline adducts with hydrohalic acids, o-cresol, resorcinol, and phosphoric acid. Formation of these adducts is useful for purification. [4] In 1870, F. S. Cloez identified and ascribed the name "eucalyptol" to the dominant portion of Eucalyptus globulus oil. [2]
The probable lethal dose of pure eucalyptus oil for an adult is in the range of 0.05 mL to 0.5 mL/per kg of body weight. [17] Because of their high body-surface-area-to-mass ratio, children are more vulnerable to poisons absorbed transdermally. Severe poisoning has occurred in children after ingestion of 4 mL to 5 mL of eucalyptus oil. [18]
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C. citriodora oil, when refined to increase its PMD content for use in insect repellents, is known in the United States as oil of lemon eucalyptus (OLE). [2] C. citriodora oil contains only 1–2% PMD, while refined OLE contains approximately up to 70% PMD. [3] Some commercial PMD products are not made from C. citriodora oil, but rather from ...