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Dr. Alexiades says that she believes keloids behave like benign tumors of the skin; the fibroblasts—the cells that make collagen—are proliferating and producing collagen out of control in keloids.
Keloids. Keloids grow extensively beyond the wound margins and tend to persist or even worsen over time. [11] They are relatively difficult to treat due to their high risk of recurrence. [9] Keloids are more common in people with darker skin tones [12] and often occur in individuals with a genetic predisposition. [13]
A keloid scar is benign and not contagious, but sometimes accompanied by severe itchiness, pain, [2] and changes in texture. In severe cases, it can affect movement of skin. In the United States, keloid scars are seen 15 times more frequently in people of sub-Saharan African descent than in people of European descent. [3]
A hypertrophic scar is a cutaneous condition characterized by deposits of excessive amounts of collagen which gives rise to a raised scar, but not to the degree observed with keloids. [1] Like keloids, they form most often at the sites of pimples, body piercings, cuts and burns. They often contain nerves and blood vessels.
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Lone excision of keloid scars, however, shows a recurrence rate close to 45%. A clinical study is currently ongoing to assess the benefits of a treatment combining surgery and laser-assisted healing in hypertrophic or keloid scars. Subcision is a process used to treat deep rolling scars left behind by acne or other skin diseases