Search results
Results From The WOW.Com Content Network
Adenylate kinase (EC 2.7.4.3) (also known as ADK or myokinase) is a phosphotransferase enzyme that catalyzes the interconversion of the various adenosine phosphates (ATP, ADP, and AMP). By constantly monitoring phosphate nucleotide levels inside the cell, ADK plays an important role in cellular energy homeostasis
Adenine nucleotide translocator (ANT), also known as the ADP/ATP translocase (ANT), ADP/ATP carrier protein (AAC) or mitochondrial ADP/ATP carrier, exchanges free ATP with free ADP across the inner mitochondrial membrane. [1] [2] ANT is the most abundant protein in the inner mitochondrial membrane and belongs to the mitochondrial carrier family ...
Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. It is composed of two linked multi-subunit complexes: the soluble catalytic core, F 1 , and the membrane-spanning component, F O , which comprises the proton channel.
Most of the ATP synthesized in the mitochondria will be used for cellular processes in the cytosol; thus it must be exported from its site of synthesis in the mitochondrial matrix. ATP outward movement is favored by the membrane's electrochemical potential because the cytosol has a relatively positive charge compared to the relatively negative ...
11740 Ensembl ENSG00000005022 ENSMUSG00000016319 UniProt P05141 Q6NVC0 P51881 RefSeq (mRNA) NM_001152 NM_007451 RefSeq (protein) NP_001143 NP_001143.2 NP_031477 Location (UCSC) Chr X: 119.47 – 119.47 Mb Chr X: 36.06 – 36.06 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse ADP/ATP translocase 2 is a protein that in humans is encoded by the SLC25A5 gene on the X chromosome. This ...
The variation in ATP levels at different stages of the cell cycle support the hypothesis that mitochondria play an important role in cell cycle regulation. [71] Although the specific mechanisms between mitochondria and the cell cycle regulation is not well understood, studies have shown that low energy cell cycle checkpoints monitor the energy ...
The ATP synthase complex exists within the mitochondrial membrane (F O portion) and protrudes into the matrix (F 1 portion). The energy derived as a result of the chemical gradient is then used to synthesize ATP by coupling the reaction of inorganic phosphate to ADP in the active site of the ATP synthase enzyme; the equation for this can be ...
The ATP Assay Concept is a well-known technique for determining the viability of cells using the assessment of ATP and a method known as "firefly luciferase". [ 5 ] Sodium-potassium ratio: Another kind of assay practices the examination of the ratio of potassium to sodium in cells to serve as an index of viability.