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Lipoblastoma is a type of rare, subcutaneous, benign, fatty tumor, [1] [2] found in infants, and children, more common in males with tendency of local recurrence ...
Lipoblasts (white arrow) and lipocytes (black arrow), in a case of lipoblastoma. Micrograph showing a lipoblast (left-bottom of image) in a liposarcoma. H&E stain.
Mesenchymal stem cells can differentiate into adipocytes, connective tissue, muscle or bone. [ 1 ] The precursor of the adult cell is termed a lipoblast , and a tumor of this cell type is known as a lipoblastoma .
[4] [5] Today Diffuse lipoblastoma is the preferred term for lipoblastomatosis. [6] [7] The tumor is rare, accounting for less than 1% of all childhood neoplasm, [8] and it has been found to be more common in males than females. [9] [8] It often presents as an asymptomatic rapidly enlarging mass, occurring more often in the soft tissues of the ...
These studies support prior epidemiologic data in humans showing a correlation between HMG I-C and mesenchymal tumors. [17] Cases have been reported where minor injuries are alleged to have triggered the growth of a lipoma, called a "post-traumatic lipoma". [18] However, the link between trauma and the development of lipomas is controversial. [19]
Lipoblastoma; 889–892 Myomatous neoplasms. M8890/0 Leiomyoma, NOS Fibroid uterus (C55.9) ... M9240/3 Mesenchymal chondrosarcoma M9241/0 Chondromyxoid fibroma
Fibroblastic and myofibroblastic tumors (FMTs) are tumors which develop from the mesenchymal stem cells which differentiate into fibroblasts (the most common cell type in connective tissue) and/or the myocytes/myoblasts that differentiate into muscle cells.
This is a mechanism through which cancer cells lose their epithelial properties resulting in a loss of cell-cell adhesion and a transition towards mesenchymal-like properties . EMT plays a diverse and essential role in adhesion, motility and morphology of cells under both normal and pathological conditions.