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This list of over 500 monoclonal antibodies includes approved and investigational drugs as well as drugs that have been withdrawn from market; consequently, the column Use does not necessarily indicate clinical usage. See the list of FDA-approved therapeutic monoclonal antibodies in the monoclonal antibody therapy page.
Schematic structure of an antibody–drug conjugate (ADC) Antibody–drug conjugates or ADCs are a class of biopharmaceutical drugs designed as a targeted therapy for treating cancer. [1] Unlike chemotherapy, ADCs are intended to target and kill tumor cells while sparing healthy cells. As of 2019, some 56 pharmaceutical companies were ...
Liposomes can carry drugs or therapeutic nucleotides and when conjugated with monoclonal antibodies, may be directed against malignant cells. Immunoliposomes have been successfully used in vivo to convey tumour-suppressing genes into tumours, using an antibody fragment against the human transferrin receptor.
Pages in category "Antibody-drug conjugates" The following 57 pages are in this category, out of 57 total. This list may not reflect recent changes. ...
This underpinned the concept of monoclonal antibodies and monoclonal drug conjugates. Ehrlich and Élie Metchnikoff received the 1908 Nobel Prize for Physiology or Medicine for providing the theoretical basis for immunology. By the 1970s, lymphocytes producing a single antibody were known, in the form of multiple myeloma – a cancer affecting ...
Antibody-drug conjugates (57 P) E. Experimental monoclonal antibodies (53 P) M. Monoclonal antibodies for tumors (140 P) U. ... Pages in category "Monoclonal antibodies"
Pages in category "Drugs that are a monoclonal antibody" The following 200 pages are in this category, out of approximately 482 total. This list may not reflect recent changes .
Immunoconjugates are antibodies conjugated (joined) to a second molecule, usually a toxin, radioisotope or label. [1]These conjugates are used in immunotherapy [citation needed] and to develop monoclonal antibody therapy as a targeted form of chemotherapy [2] when they are often known as antibody-drug conjugates.