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Schematic structure of an antibody–drug conjugate (ADC) Antibody–drug conjugates or ADCs are a class of biopharmaceutical drugs designed as a targeted therapy for treating cancer. [ 1 ] Unlike chemotherapy , ADCs are intended to target and kill tumor cells while sparing healthy cells.
The Wilkinson ADC was designed by Denys Wilkinson in 1950. The Wilkinson ADC is based on the comparison of an input voltage with that produced by a charging capacitor. The capacitor is allowed to charge until a comparator determines it matches the input voltage. Then, the capacitor is discharged linearly by using a constant current source. The ...
Instead of using the comparators in a flash ADC only once, the folding ADC re-uses the comparators multiple times during a ramp input signal. If a m -times folding circuit is used in an n -bit ADC, the actual number of comparator can be reduced from 2 n − 1 {\displaystyle 2^{n}-1} to 2 n m {\displaystyle {\frac {2^{n}}{m}}} (there is always ...
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An integrating ADC is a type of analog-to-digital converter that converts an unknown input voltage into a digital representation through the use of an integrator.In its basic implementation, the dual-slope converter, the unknown input voltage is applied to the input of the integrator and allowed to ramp for a fixed time period (the run-up period).
Buck was founded in 2004 [1] by Jeff Ellermeyer, Ryan Honey, and Orion Tait in Los Angeles as a motion graphics and animation company. In 2006, they opened their second office in New York, headed by Tait. [3]
The ADC market segment became fragmented into two general areas: 1) general network optimization; and 2) application/framework specific optimization. Both types of devices improve performance, but the latter is usually more aware of optimization strategies that work best with a particular application framework, focusing on ASP.NET or AJAX ...
Meta Platforms, Inc., [9] doing business as Meta, [10] and formerly named Facebook, Inc., and TheFacebook, Inc., [11] [12] is an American multinational technology conglomerate based in Menlo Park, California. The company owns and operates Facebook, Instagram, Threads, and WhatsApp, among other products and services. [13]