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On average, statins can lower LDL cholesterol by 1.8 mmol/L (70 mg/dL), which translates into an estimated 60% decrease in the number of cardiac events (heart attack, sudden cardiac death) and a 17% reduced risk of stroke after long-term treatment. [36] A greater benefit is observed with high-intensity statin therapy. [37]
Most people want to live a long, healthy life, ... But research on statins like atorvastatin has only found a small decrease in the risk of dying from heart disease on the medication.
Statins appear to be effective at preventing cardiovascular disease and death in older adults, according to new research. Most clinical trials evaluating statins have not included people 75 and ...
Impact of statins on cholesterol, heart disease risk Cheng-Han Chen, MD , of Saddleback Medical Center, CA, not involved in the study, explained that cholesterol in the body comes from two sources.
In studies using standard doses, statins have been found to lower LDL-C by 18% to 55%, depending on the specific statin being used. A risk exists of muscle damage (myopathy and rhabdomyolysis) with statins. Hypercholesterolemia is not a risk factor for mortality in persons older than 70 years and risks from statin drugs are more increased after ...
SAAM may affect people after long-term statin use even if they had no previous muscular side effects. [4] A differentiating feature between this and more benign statin side effects is SAAM typically has a late onset. While muscle pain (myalgia) is seen in 9-20% of patients treated with statins, it typically occurs in the first month of treatment.
More than one third of women believe that doctors are too aggressive when it comes to statin medication, versus 28% of men, and 20% would discontinue statin treatment without consulting their ...
This is a major piece of evidence that statins work in another way than the lowering of cholesterol (called pleiotropic effects). [ 35 ] Simvastatin is an effective serum lipid -lowering drug that can decrease low density lipoprotein (LDL) levels by up to 50%.