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Autocrine signaling is a special case of paracrine signaling where the secreting cell has the ability to respond to the secreted signaling molecule. [9] Synaptic signaling is a special case of paracrine signaling (for chemical synapses ) or juxtacrine signaling (for electrical synapses ) between neurons and target cells.
Autocrine signaling is a form of cell signaling in which a cell secretes a hormone or chemical messenger (called the autocrine agent) that binds to autocrine receptors on that same cell, leading to changes in the cell. [1] This can be contrasted with paracrine signaling, intracrine signaling, or classical endocrine signaling.
The endocrine system [1] is a messenger system in an organism comprising feedback loops of hormones that are released by internal glands directly into the circulatory system and that target and regulate distant organs. In vertebrates, the hypothalamus is the neural control center for all endocrine systems.
In biochemistry and pharmacology, receptors are chemical structures, composed of protein, that receive and transduce signals that may be integrated into biological systems. [1] These signals are typically chemical messengers [ nb 1 ] which bind to a receptor and produce physiological responses such as change in the electrical activity of a cell .
An antagonist is a chemical that acts within the body to reduce the physiological activity of another chemical substance (such as an opiate); especially one that opposes the action on the nervous system of a drug or a substance occurring naturally in the body by combining with and blocking its nervous receptor.
In contrast, classic hormones, such as insulin, are secreted from discrete glands such as the pancreas. [13] The current terminology refers to cytokines as immunomodulating agents . A contributing factor to the difficulty of distinguishing cytokines from hormones is that some immunomodulating effects of cytokines are systemic ( i.e. , affecting ...
The two main chemical messengers of the sympathoadrenal system are norepinephrine and epinephrine (also called noradrenaline and adrenaline respectively). These chemicals are created by the adrenal glands after receiving neuronal signals from the sympathetic nervous system. The different physiological effects of these chemicals depend on the ...
Like the average neuron, these cells conduct electrical impulses along the axon but unlike these neurons, neurosecretion produces neurohormones that are released into the body’s circulation. Combining the properties of the nervous and endocrine, these cells have the capacity to affect nerves through chemical messengers. [4]