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The proportion of AST to ALT in hepatocytes is about 2.5:1, but because AST is removed from serum by the liver sinusoidal cells twice as quickly (serum half-life t 1/2 = 18 hr) compared to ALT (t 1/2 = 36 hr), so the resulting serum levels of AST and ALT are about equal in healthy individuals, resulting in a normal AST/ALT ratio around 1.
Ischemic hepatopathy (shock liver): AST and ALT > 50 times the URL (in addition the lactate dehydrogenase is often markedly elevated) [15] Chronic hepatitis C virus infection: Wide variability, typically normal to less than twice the URL, rarely more than 10 times the URL
Alanine transaminase (ALT), also known as alanine aminotransferase (ALT or ALAT), formerly serum glutamate-pyruvate transaminase (GPT) or serum glutamic-pyruvic transaminase (SGPT), is a transaminase enzyme (EC 2.6.1.2) that was first characterized in the mid-1950s by Arthur Karmen and colleagues. [1]
In pregnancy, ALT levels would rise during the second trimester. In one of the studies, measured ALT levels in pregnancy-related conditions such as hyperemesis gravidarum was 103.5 IU/L, pre-eclampsia was 115, HELLP syndrome was 149. ALT levels would reduce by greater than 50% in three days after child delivery.
In the IBM PC Bios typing an Alt code greater than 255 produced the same as that number modulo 256. [3] Some applications retained this behavior, while others (in particular applications using the Windows RichEdit control, such as WordPad and PSPad ) made numbers from 256 to 65,535 produce the corresponding Unicode character. [ 4 ]
5 Carriage Return (accompanied by line feed) is used as "end of line" character by Windows, DOS, and most minicomputers other than Unix- / Linux-based systems 6 Control-O has been the "discard output" key. Output is not sent to the terminal, but discarded, until another Control-o is typed.
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