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  2. Standardized uptake value - Wikipedia

    en.wikipedia.org/wiki/Standardized_Uptake_Value

    3-dimensional [18 F]FDG-PET image with 3D ROI generated by a threshold based algorithm.The blue dot in the MIP image bottom right marks the maximum SUV within the ROI.. The standardized uptake value (SUV) is a nuclear medicine term, used in positron emission tomography (PET) as well as in modern calibrated single photon emission tomography (SPECT) imaging for a semiquantitative analysis. [1]

  3. PET response criteria in solid tumors - Wikipedia

    en.wikipedia.org/wiki/PET_response_criteria_in...

    >30% increase in 18F-FDG SUL peak, with >0.8 SUL units increase in tumor SUV peak from the baseline scan in pattern typical of tumor and not of infection/treatment effect. or Visible increase in the extent of 18F-FDG tumor uptake. or New 18F-FDG avid lesions which are typical of cancer and not related to treatment effect or infection.

  4. Positron emission tomography - Wikipedia

    en.wikipedia.org/wiki/Positron_emission_tomography

    PET scanning does this by using radiolabelled molecular probes that have different rates of uptake depending on the type and function of tissue involved. Regional tracer uptake in various anatomic structures can be visualized and relatively quantified in terms of injected positron emitter within a PET scan. [citation needed]

  5. Fluciclovine (18F) - Wikipedia

    en.wikipedia.org/wiki/Fluciclovine_(18F)

    Fluciclovine is a [18 F]-tagged synthetic analog of the amino acid L-leucine.[11] [12] FACBC uptake by the tumor is related to functional activity of two amino acid transporters, [13] specifically sodium-dependent system ASC, with a lesser contribution by sodium-independent system L. [12] Although it is handled by the amino acid transporter system, it does not undergo terminally incorporative ...

  6. Hypermetabolism - Wikipedia

    en.wikipedia.org/wiki/Hypermetabolism

    Shown above is a PET scan of hypermetabolic Astrocytoma in the brain. Many different illnesses can cause an increase in metabolic activity as the body combats illness and disease in order to heal itself. Hypermetabolism is a common symptom of various pathologies. Some of the most prevalent diseases characterized by hypermetabolism are listed below.

  7. Warburg effect (oncology) - Wikipedia

    en.wikipedia.org/wiki/Warburg_effect_(oncology)

    Diagnostically the increased glucose consumption by cancer cells resulting from the Warburg effect is the basis for tumor detection in a PET scan, in which an injected radioactive glucose analog is detected at higher concentrations in malignant cancers than in other tissues. [5]

  8. Metabolic trapping - Wikipedia

    en.wikipedia.org/wiki/Metabolic_trapping

    Metabolic trapping is the mechanism underlying the scan, [4] an effective tool for detecting tumors, as there is a greater uptake of the target molecule by tumor tissue than by normal tissue. In order to use it as a diagnostic tool in medicine, scientists have studied the trapping of radioactive molecules within different tissues throughout the ...

  9. Krenning score - Wikipedia

    en.wikipedia.org/wiki/Krenning_score

    grade uptake intensity of neuroendocrine tumors The Krenning score [ 1 ] is used to grade the uptake intensity of neuroendocrine tumors on somatostatin receptor imaging such as octreotide scan . [ further explanation needed ] Typically, peptide receptor radionuclide therapy (PRRT) is considered when the Krenning score is greater than 2.