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[10] [11] No other interstitial cell within the testes has a nucleus or cytoplasm with these characteristics, making identification relatively easy. While any age is susceptible to a Leydig cell tumour, Leydig cell tumours are more common in people aged 5 to 10 and 30 to 35. [12] A Leydig cell tumour in a child usually causes precocious puberty ...
Leydig cell tumour, also Leydig cell tumor (US spelling), (testicular) interstitial cell tumour and (testicular) interstitial cell tumor (US spelling), is a member of the sex cord-stromal tumour group [2] of ovarian and testicular cancers. It arises from Leydig cells. While the tumour can occur at any age, it occurs most often in young adults.
The testes grow in response to the start of spermatogenesis. Size depends on lytic function, sperm production (amount of spermatogenesis present in testis), interstitial fluid, and Sertoli cell fluid production. The testicles are fully descended before the male reaches puberty.
Interstitial cell refers to any cell that lies in the spaces between the functional cells of a tissue. Examples include: Interstitial cell of Cajal (ICC) Leydig cells, cells present in the male testes responsible for the production of androgen (male sex hormone) A portion of the stroma of ovary; Certain cells in the pineal gland; Renal ...
Testosterone is produced by interstitial cells, also known as Leydig cells, which reside adjacent to the seminiferous tubules. Seminiferous epithelium is sensitive to elevated temperature in humans and some other species, and will be adversely affected by temperatures as high as normal body temperature.
[86] [47] Non-immune cells of the testis such as Sertoli cells and Leydig cells also able to respond to bacteria. [63] [89] During a bacterial infection, testosterone levels and the amount of testicular interstitial fluid are reduced. [39] Neutrophils enter the testis about 12 hours after infection. [39]
Sertoli cells function to nourish the developing sperm cells. They secrete androgen-binding protein, a binding protein which increases the concentration of testosterone. There are two types: convoluted and straight, convoluted toward the lateral side, and straight as the tubule comes medially to form ducts that will exit the testis.
Sertoli cells are a type of sustentacular "nurse" cell found in human testes which contribute to the process of spermatogenesis (the production of sperm) as a structural component of the seminiferous tubules. They are activated by follicle-stimulating hormone (FSH) secreted by the adenohypophysis and express FSH receptor on their membranes.