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Scleroderma is a group of autoimmune diseases that may result in changes to the skin, blood vessels, muscles, and internal organs. [ 2 ] [ 6 ] [ 8 ] The disease can be either localized to the skin or involve other organs, as well. [ 2 ]
Systemic scleroderma, or systemic sclerosis, is an autoimmune rheumatic disease characterised by excessive production and accumulation of collagen, called fibrosis, in the skin and internal organs and by injuries to small arteries. There are two major subgroups of systemic sclerosis based on the extent of skin involvement: limited and diffuse ...
In reaction to the lack of awareness of the disease in the medical community, she went on to found the Scleroderma Research Foundation in 1987, [2] an organization dedicated to finding a cure. [4] According to the New York Times, "Ms. Monsky's activities generated more than $14 million for research and helped expand understanding of the disease ...
Scleromyositis, is an autoimmune disease (a disease in which the immune system attacks the body). People with scleromyositis have symptoms of both systemic scleroderma and either polymyositis or dermatomyositis, and is therefore considered an overlap syndrome.
Systemic sclerosis (progressive systemic scleroderma), a rare, chronic disease which affects the skin, and in some cases also blood vessels and internal organs. Tuberous sclerosis, a rare genetic disease which affects multiple systems.
The surviving spouse’s own adult children may subsequently inherit everything, leaving out stepchildren. Laws guaranteeing a spousal elective share may also result in an uneven distribution of ...
Systemic autoimmune diseases include coeliac disease, lupus erythematosus, Sjögren syndrome, scleroderma, rheumatoid arthritis, cryoglobulinemic vasculitis, and dermatomyositis. These conditions tend to be associated with autoantibodies to antigens which are not tissue specific.
Morphea is a form of scleroderma that is more common in women than men, in a ratio 3:1. [17] Morphea occurs in childhood as well as in adult life. [ 3 ] Morphea is an uncommon condition that is thought to affect 2 to 4 in 100,000 people. [ 18 ]