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In organic chemistry, an azo coupling is an reaction between a diazonium compound (R−N≡N +) and another aromatic compound that produces an azo compound (R−N=N−R’).In this electrophilic aromatic substitution reaction, the aryldiazonium cation is the electrophile, and the activated carbon (usually from an arene, which is called coupling agent), serves as a nucleophile.
In this process, the diazonium compound is attacked by, i.e., coupled to, electron-rich substrates. When the coupling partners are arenes such as anilines and phenols, the process is an example of electrophilic aromatic substitution: [ArN 2] + + Ar'H → ArN 2 Ar' + H + The deep colors of the dyes reflects their extended conjugation.
The pill, referred to as LOY-002, aims to reduce aging in dogs by combating the metabolic changes that can arise with age, such as diabetes mellitus (insulin resistance). It’s a beef-flavored ...
Azo compounds are organic compounds bearing the functional group diazenyl (R−N=N−R′, in which R and R′ can be either aryl or alkyl groups). IUPAC defines azo compounds as: "Derivatives of diazene (diimide), HN=NH , wherein both hydrogens are substituted by hydrocarbyl groups, e.g. PhN=NPh azobenzene or diphenyldiazene.", where Ph stands ...
The latter easily converts to zidovudine 4 (also known as azidothymidine or AZT), an important antiviral drug, used among others in the treatment of AIDS. [ 17 ] [ 18 ] [ 19 ] Another example of pharmaceutical application of DEAD-assisted Mitsunobu reaction is the synthesis of bis[(pivaloyloxy)methyl [PIVz] derivative of 2'-deoxy-5 ...
The Cost of Pet Insurance vs. Paying Out-of-Pocket. To understand the value of pet insurance, let's compare the costs: Routine Care: Annual check-up: Up to $250. Bloodwork: Up to $200. X-rays: Up ...