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Anti-MAG peripheral neuropathy is a specific type of peripheral neuropathy in which the person's own immune system attacks cells that are specific in maintaining a healthy nervous system. As these cells are destroyed by antibodies , the nerve cells in the surrounding region begin to lose function and create many problems in both sensory and ...
Rituximab, sold under the brand name Rituxan among others, is a monoclonal antibody medication used to treat certain autoimmune diseases and types of cancer. [18] It is used for non-Hodgkin lymphoma, chronic lymphocytic leukemia (in children and adults, but not recommended in elderly patients), rheumatoid arthritis, granulomatosis with polyangiitis, idiopathic thrombocytopenic purpura ...
Rituximab: IV: Anti-CD20 antibody. CD20-positive B cell non-Hodgkin lymphoma, chronic lymphocytic leukaemia, rheumatoid arthritis, granulomatosis with polyangiitis ...
Various, including anti-MAG Confirmed 1-2 per 100,000 [59] Guillain-Barré syndrome: Peripheral nerves Various, including anti-GM1, anti-GD1a Confirmed 1-2 per 100,000 [60] Hashimoto's encephalopathy: Brain Anti-thyroid (TPO, Tg) Probable Rare [61] Idiopathic inflammatory demyelinating diseases: Central nervous system Varies Probable
Immunosuppressive drugs are often of the cytotoxic (chemotherapy) class, including rituximab (Rituxan) which targets B cells, and cyclophosphamide, a drug which reduces the function of the immune system. Ciclosporin has also been used in CIDP but with less frequency as it is a newer approach. [40]
Myelin-associated glycoprotein (MAG, Siglec-4) is a type 1 transmembrane protein glycoprotein localized in periaxonal Schwann cell and oligodendrocyte membranes, where it plays a role in glial-axonal interactions.
FCM, or FMC in the context of chemotherapy is an acronym for a chemotherapy regimen that is used in the treatment of indolent B cell non-Hodgkin's lymphomas.In combination with Rituximab, this regimen is called R-FCM or R-FMC, or FCM-R, FMC-R.
FM in the context of chemotherapy means a chemotherapy regimen used as first-line therapy in indolent lymphomas.In combination with rituximab it is called R-FM or RFM or FM-R or FMR.