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Psoriatic arthritis (PsA) is a long-term inflammatory arthritis that occurs in people affected by the autoimmune disease psoriasis. [1] [2] The classic features of psoriatic arthritis include dactylitis (sausage-like appearance), skin lesions, and nail lesions. [3]
Approximately 40–50% of individuals with psoriatic arthritis have the HLA-B27 genotype. [9] HLA-B27 is implicated in other types of seronegative spondyloarthropathy, such as reactive arthritis, acute anterior uveitis, iritis, Crohn's and ulcerative colitis associated spondyloarthritis. The shared association with HLA-B27 leads to increased ...
Usually, psoriatic arthritis begins with some joint swelling like a finger or a toe, says Bauer. Dactylitis, which describes a digit that’s completely swollen like a sausage, is a common sign of ...
Aggressive psoriatic arthritis erosions can result in the articular surface of the proximal bone of the joint being destroyed and taking on the look of a "pencil in cup." [27] Laboratory abnormalities in spondyloarthritis are nonspecific and less effective for diagnosing a specific disease than clinical presentation.
Reference ranges (reference intervals) for blood tests are sets of values used by a health professional to interpret a set of medical test results from blood samples. Reference ranges for blood tests are studied within the field of clinical chemistry (also known as "clinical biochemistry", "chemical pathology" or "pure blood chemistry"), the ...
For example, psoriatic arthritis can cause both peripheral and axial symptoms. [7] Likewise, reactive arthritis can transform into chronic axial spondyloarthritis. [8] All are considered inflammatory rheumatic disorders because they involve immune system-mediated attacks on the joints, muscles, bones and organs. [9]
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