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In hematology, red cell agglutination or autoagglutination is a phenomenon in which red blood cells clump together, forming aggregates. It is caused by the surface of the red cells being coated with antibodies .
This image explains agglutination in the blood. Agglutination is the clumping of particles. The word agglutination comes from the Latin agglutinare (glueing to).. Agglutination is a reaction in which particles (as red blood cells or bacteria) suspended in a liquid collect into clumps usually as a response to a specific antibody.
Each sample is incubated against a wide range of RBCs that together exhibit a full range of surface antigens (i.e. blood types). Cross matching; The indirect Coombs test is used to test a sample of the recipient's serum for antibodies against a sample of the blood donor's RBCs. This is sometimes called cross-matching blood.
A slide coagulase test is run with a negative control to rule out autoagglutination. Two drops of saline are put onto the slide labeled with sample number, Test (T) and control (C). The two saline drops are emulsified with the test organism using a wire loop, straight wire, or wooden stick.
An anticancer drug is coupled to an antibody that targets a specific tumor antigen (or protein) that, ideally, is only found in or on tumor cells.Antibodies attach themselves to the antigens on the surface of cancerous cells.
An overview of the different components included in the field of chemical biology. Chemical biology is a scientific discipline between the fields of chemistry and biology.The discipline involves the application of chemical techniques, analysis, and often small molecules produced through synthetic chemistry, to the study and manipulation of biological systems. [1]
Oligonucleotides are short DNA or RNA molecules, oligomers, that have a wide range of applications in genetic testing, research, and forensics.Commonly made in the laboratory by solid-phase chemical synthesis, [1] these small fragments of nucleic acids can be manufactured as single-stranded molecules with any user-specified sequence, and so are vital for artificial gene synthesis, polymerase ...
Bioanalysis is a sub-discipline of analytical chemistry covering the quantitative measurement of xenobiotics (drugs and their metabolites, and biological molecules in unnatural locations or concentrations) and biotics (macromolecules, proteins, DNA, large molecule drugs, metabolites) in biological systems.