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This disease is characterised by multifocal stenosing ulceration of the small intestine. The ulcers are circular or irregular in shape and their margins are always clear. The lesions involve only the mucosa and submucosa and are confined to the jejunum and proximal ileum. The intervening mucosa appears normal. Nonspecific inflammatory changes ...
Peptic ulcer disease is when the inner part of the stomach's gastric mucosa (lining of the stomach), the first part of the small intestine, or sometimes the lower esophagus, gets damaged. An ulcer in the stomach is called a gastric ulcer , while one in the first part of the intestines is a duodenal ulcer . [ 1 ]
Within the small intestine there are multiple small shallow ulcers which may be linear or concentric. [5] Stenosis of the small bowel may be present due to healing of these ulcers. The ulcers resemble those associated with non steroidal use but occur in the absence of the use of these drugs. [citation needed]
Lower endoscopy to evaluate the rectum and distal large intestine (sigmoidoscopy) or entire colon and end of the small intestine (colonoscopy) for ulcers and inflammation; Although ulcerative colitis is a disease of unknown causation, inquiry should be made as to unusual factors believed to trigger the disease. [19]
The above ulcer seen after endoscopic clipping. Upper endoscopy within 24 hours is the recommended treatment. [15] [23] The benefits versus risks of placing a nasogastric tube in those with upper gastrointestinal bleeding are not well known. [15]
Surgical treatment is usually required due to the likelihood of stenosis or complete occlusion of the small intestine. [17] Ischemic damage can range from mucosal infarction, which is limited only to the mucosa; mural infarction of the mucosa and underlying submucosa; to transmural infarction of the full thickness of the gastrointestinal wall.
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