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Overlying this cap structure is the ectomesenchyme, which is attached to the mesodermal tissue known as the dental papilla superiorly, and lies within the epithelial concavity. [ 3 ] Various types of differentiation occur at this stage; such as cytodifferentiation, histodifferentiation and morphodifferentation .
Both the dental papilla and the tooth sac are not structurally defined in the bud stage, and will become more defined in subsequent stages (Cap and Bell stages). The interaction and signalling between the enamel organ and the surrounding mesenchymal cells play an important role in the later stages of tooth development. [2] Each dental arch will ...
At this point, the tooth bud grows around the ectomesenchymal aggregation, taking on the appearance of a cap, and becomes the enamel (or dental) organ covering the dental papilla. A condensation of ectomesenchymal cells called the dental sac or follicle surrounds the enamel organ and limits the dental papilla. Eventually, the enamel organ will ...
In animal tooth development, the inner enamel epithelium, also known as the internal enamel epithelium, is a layer of columnar cells located on the rim nearest the dental papilla of the enamel organ in a developing tooth. This layer is first seen during the cap stage, in which these inner enamel epithelium cells are pre-ameloblast cells.
The tooth bud (sometimes called the tooth germ) is an aggregation of cells that eventually forms a tooth and is organized into three parts: the enamel organ, the dental papilla and the dental follicle. [3] The enamel organ is composed of the outer enamel epithelium, inner enamel epithelium, stellate reticulum and stratum intermedium. [3]
Together the epithelial enamel organ and ectomesenchymal dental papilla and follicle form the tooth germ. The dental papilla is the origin of dental pulp. Cells at the periphery of the dental papilla undergo cell division and differentiation to become odontoblasts. Pulpoblasts form in the middle of the pulp. This completes the formation of the ...
Reversal of nutrition - as long as the ameloblasts are in contact with the dental papilla, they receive nutrient material from the blood vessels of the tissue, but due to formation of this dentin the original source of nutrition is cut off and the ameloblasts are supplied by capillaries penetrating the outer enamel epithelium. This change in ...
Odontoblasts first appear at sites of tooth development at 17–18 weeks in utero and remain present until death unless killed by bacterial or chemical attack, or indirectly through other means such as heat or trauma (e.g. during dental procedures). Odontoblasts were originally the outer cells of the dental papilla.