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In embryology and prenatal development, the dental papilla is a condensation of ectomesenchymal cells called odontoblasts, seen in histologic sections of a developing tooth. It lies below a cellular aggregation known as the enamel organ. The dental papilla appears after 8–10 weeks of intra uteral life.
The dental papilla contains cells that develop into odontoblasts, which are dentin-forming cells. [2] Additionally, the junction between the dental papilla and inner enamel epithelium determines the crown shape of a tooth. [1] Mesenchymal cells within the dental papilla are responsible for formation of tooth pulp.
Both the dental papilla and the tooth sac are not structurally defined in the bud stage, and will become more defined in subsequent stages (Cap and Bell stages). The interaction and signalling between the enamel organ and the surrounding mesenchymal cells play an important role in the later stages of tooth development. [2] Each dental arch will ...
Tooth development is the complex process by which teeth form from embryonic cells, grow, ... the enamel organ, the dental papilla and the dental follicle. [27]
Odontoblasts form approximately 4 μm of predentin daily during tooth development. [ 1 ] During secretion after differentiation from the outer cells of the dental papilla, it is noted that it is polarized so its nucleus is aligned away from the newly formed dentin, with its Golgi complex and endoplasmic reticulum towards the dentin reflecting ...
In the inductive stage, the morphodifferentiation phase the shape of the crown is determined by the bell stage of tooth development. There is a basal lamina between the IEE and the dental papilla. [2] At this time, the dentin is not mineralized. The IEE cuboidal or low columnar with centralized nuclei and poorly developed Golgi complexes.
It is widely accepted that there is a factor within the tissues of the first branchial arch that is necessary for the development of teeth. [2] The tooth bud (sometimes called the tooth germ) is an aggregation of cells that eventually forms a tooth and is organized into three parts: the enamel organ, the dental papilla and the dental follicle. [3]
The Hertwig epithelial root sheath (HERS) or epithelial root sheath is a proliferation of epithelial cells located at the cervical loop of the enamel organ in a developing tooth. Hertwig epithelial root sheath initiates the formation of dentin in the root of a tooth by causing the differentiation of odontoblasts from the dental papilla.