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  2. Effects of long-term benzodiazepine use - Wikipedia

    en.wikipedia.org/wiki/Effects_of_long-term...

    [113] [114] Long-term use of benzodiazepines in the elderly can lead to a pharmacological syndrome with symptoms including drowsiness, ataxia, fatigue, confusion, weakness, dizziness, vertigo, syncope, reversible dementia, depression, impairment of intellect, psychomotor and sexual dysfunction, agitation, auditory and visual hallucinations ...

  3. Valsartan - Wikipedia

    en.wikipedia.org/wiki/Valsartan

    Valsartan, sold under the brand name Diovan among others, is a medication used to treat high blood pressure, heart failure, and diabetic kidney disease. [8] It belongs to a class of medications referred to as angiotensin II receptor blockers (ARBs).

  4. Delirium - Wikipedia

    en.wikipedia.org/wiki/Delirium

    Delirium (formerly acute confusional state, an ambiguous term that is now discouraged) [1] is a specific state of acute confusion attributable to the direct physiological consequence of a medical condition, effects of a psychoactive substance, or multiple causes, which usually develops over the course of hours to days.

  5. Cardiovascular agents - Wikipedia

    en.wikipedia.org/wiki/Cardiovascular_agents

    Antihypertensive agents comprise multiple classes of compounds that are intended to manage hypertension (high blood pressure). Antihypertensive therapy aims to maintain a blood pressure goal of <140/90 mmHg in all patients, as well as to prevent the progression or recurrence of cardiovascular diseases (CVD) in hypertensive patients with established CVD. [2]

  6. Valsartan/hydrochlorothiazide - Wikipedia

    en.wikipedia.org/wiki/Valsartan/hydrochlorothiazide

    Valsartan/hydrochlorothiazide, sold under the brand name Diovan HCT among others, is a medication used to treat high blood pressure when valsartan is not sufficient. [6] It is a combination of valsartan, an angiotensin receptor blocker with hydrochlorothiazide, a diuretic. [7] It is taken by mouth. [7] Common side effects include dizziness and ...

  7. Sundowning - Wikipedia

    en.wikipedia.org/wiki/Sundowning

    Stress, hypometabolism, and oxidative damage may decrease physiologic reserve in the elderly and can lead to a decrease in neuron energy production and an increase in neuron damage. [12] Thioredoxin reductase is an antioxidant that neutralizes oxidative free radicals that can cause cell death. The brain is vulnerable to oxidative free radicals ...

  8. Discovery and development of angiotensin receptor blockers

    en.wikipedia.org/wiki/Discovery_and_development...

    Valsartan, first marketed by Novartis, is a nonheterocyclic ARB, where the imidazole of losartan has been replaced by an acylated amino acid. [ 1 ] Irbesartan was developed by Sanofi Research and is longer acting than valsartan and losartan and it has an imidazolinone ring where a carbonyl group functions as a hydrogen bond acceptor instead of ...

  9. Wernicke–Korsakoff syndrome - Wikipedia

    en.wikipedia.org/wiki/Wernicke–Korsakoff_syndrome

    It mainly causes vision changes, ataxia and impaired memory. [2] The cause of the disorder is thiamine (vitamin B 1) deficiency. This can occur due to Wernicke encephalopathy, eating disorders, malnutrition, and alcohol abuse. These disorders may manifest together or separately. WKS is usually secondary to prolonged alcohol abuse.