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(photo from 1975 plague victim) A map of the Byzantine Empire in 550 (a decade after the Plague of Justinian) with Justinian's conquests shown in green The plague of Justinian or Justinianic plague (AD 541–549) was an epidemic that afflicted the entire Mediterranean Basin, Europe, and the Near East, severely affecting the Sasanian Empire and ...
Plague of Justinian: Bubonic plague 15–100 million 25–60% of European population [5] 541–549 North Africa, Europe, and Western Asia 3 HIV/AIDS pandemic: HIV/AIDS: 44 million (as of 2025) [a] 1981–present [6] Worldwide 1 Black Death: Bubonic plague: 75-200 Miliion 30–60% of European population [7] 1346–1353 Europe, Asia, and North ...
The first plague pandemic was the first historically recorded Old World pandemic of plague, the contagious disease caused by the bacterium Yersinia pestis. Also called the early medieval pandemic, it began with the Plague of Justinian in 541 and continued until 750 or 767. At least fifteen to eighteen major waves of plague following the ...
The Black Death ravaged much of the Islamic world. [55] Plague was present in at least one location in the Islamic world virtually every year between 1500 and 1850. [56] Plague repeatedly struck the cities of North Africa. Algiers lost 30,000–50,000 to it in 1620–1621, and again in 1654–1657, 1665, 1691, and 1740–1742. [57]
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The Black Death was a bubonic plague pandemic that occurred in Europe from 1346 to 1353. It was one of the most fatal pandemics in human history; as many as 50 million people [ 2 ] perished, perhaps 50% of Europe's 14th century population. [ 3 ]
541–542: First pandemic of bubonic plague (Plague of Justinian) hits Constantinople and the rest of Byzantine Empire. 543/544: One of Justinian's edict leads to the Three-Chapter Controversy; 545: Nubian Kingdom of Nobatia converts to Christianity. Mid-6th century – Cassiodorus founds a cenobitic monastery and scriptorium at Vivarium in Italy
The second plague pandemic was a major series of epidemics of plague that started with the Black Death, which reached medieval Europe in 1346 and killed up to half of the population of Eurasia in the next four years. It followed the first plague pandemic that began in the 6th century with the Plague of Justinian, but had