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Radiolysis of intracellular water by ionizing radiation creates peroxides, which are relatively stable precursors to hydroxyl radicals. 60%–70% of cellular DNA damage is caused by hydroxyl radicals, [3] yet hydroxyl radicals are so reactive that they can only diffuse one or two molecular diameters before reacting with cellular components.
Ionizing radiation has been known to cause damage to cellular components such as proteins, lipids, and nucleic acids. It has also been known to cause DNA double-strand breaks . Accumulation of DNA double strand breaks can lead to cell cycle arrest in somatic cells and cause cell death .
Exposure to high doses of radiation causes DNA damage, later creating serious and even lethal chromosomal aberrations if left unrepaired. Ionizing radiation can produce reactive oxygen species, and does directly damage cells by causing localized ionization events. The former is very damaging to DNA, while the latter events create clusters of ...
Ionizing radiation causes DNA damage, and cancer can develop as a result, he explains. The bottom line. In May 2011, IARC classified radio-frequency electromagnetic fields (RF-EMF) as possibly ...
Radiation hormesis is the conjecture that a low level of ionizing radiation (i.e., near the level of Earth's natural background radiation) helps "immunize" cells against DNA damage from other causes (such as free radicals or larger doses of ionizing radiation), and decreases the risk of cancer. The theory proposes that such low levels activate ...
Radiobiology is the study of the action of ionizing radiation on living things, including the health effects of radiation in humans. High doses of ionizing radiation can cause damage to living tissue such as radiation burning and harmful mutations such as causing cells to become cancerous, and can lead to health problems such as radiation ...
Ionizing radiation is used in a wide variety of fields such as medicine, nuclear power, research, and industrial manufacturing, but is a health hazard if proper measures against excessive exposure are not taken. Exposure to ionizing radiation causes cell damage to living tissue and organ damage.
In human cells, both normal metabolic activities and environmental factors such as radiation can cause DNA damage, resulting in tens of thousands of individual molecular lesions per cell per day. [2] Many of these lesions cause structural damage to the DNA molecule and can alter or eliminate the cell's ability to transcribe the gene that the ...