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  2. DNA profiling - Wikipedia

    en.wikipedia.org/wiki/DNA_profiling

    DNA profiling (also called DNA fingerprinting and genetic fingerprinting) is the process of determining an individual's deoxyribonucleic acid characteristics. DNA analysis intended to identify a species, rather than an individual, is called DNA barcoding .

  3. Amplified fragment length polymorphism - Wikipedia

    en.wikipedia.org/wiki/Amplified_fragment_length...

    Amplified fragment length polymorphism (AFLP-PCR or AFLP) is a PCR-based tool used in genetics research, DNA fingerprinting, and in the practice of genetic engineering. Developed in the early 1990s by Pieter Vos, [ 1 ] AFLP uses restriction enzymes to digest genomic DNA , followed by ligation of adaptors to the sticky ends of the restriction ...

  4. Variants of PCR - Wikipedia

    en.wikipedia.org/wiki/Variants_of_PCR

    Analysis of smaller VNTR segments known as short tandem repeats (or STRs) is the basis for DNA fingerprinting databases such as CODIS. Asymmetric PCR preferentially amplifies one strand of a double-stranded DNA target. It is used in some sequencing methods and hybridization probing to generate one DNA strand as product. Thermocycling is carried ...

  5. Variable number tandem repeat - Wikipedia

    en.wikipedia.org/wiki/Variable_number_tandem_repeat

    A single strand of DNA from each individual is displayed in which there is tandem repeat sequence that the individuals share. The sequence presence is a VNTR because one individual has five repeats, while the other has seven repeats (number of repeats varies in different individuals).

  6. STR analysis - Wikipedia

    en.wikipedia.org/wiki/STR_analysis

    STR analysis is a tool in forensic analysis that evaluates specific STR regions found on nuclear DNA. The variable (polymorphic) nature of the STR regions that are analyzed for forensic testing intensifies the discrimination between one DNA profile and another. [3] Scientific tools such as FBI approved STRmix incorporate this research technique.

  7. DNA - Wikipedia

    en.wikipedia.org/wiki/DNA

    The orientation of the 3′ and 5′ carbons along the sugar-phosphate backbone confers directionality (sometimes called polarity) to each DNA strand. In a nucleic acid double helix, the direction of the nucleotides in one strand is opposite to their direction in the other strand: the strands are antiparallel. The asymmetric ends of DNA strands ...

  8. Eukaryotic DNA replication - Wikipedia

    en.wikipedia.org/wiki/Eukaryotic_DNA_replication

    While the yeast pre-RC forms a closed DNA complex, [35] [36] [46] the human pre-RC forms an open complex. [47] At the transition of the G 1 stage to the S phase of the cell cycle, S phase–specific cyclin-dependent protein kinase (CDK) and Cdc7/Dbf4 kinase (DDK) transform the inert pre-RC into an active complex capable of assembling two ...

  9. Nucleic acid hybridization - Wikipedia

    en.wikipedia.org/wiki/Nucleic_acid_hybridization

    Fluorescence in situ hybridization (FISH) is a laboratory method used to detect and locate a DNA sequence, often on a particular chromosome. [4]In the 1960s, researchers Joseph Gall and Mary Lou Pardue found that molecular hybridization could be used to identify the position of DNA sequences in situ (i.e., in their natural positions within a chromosome).

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