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  2. PDE5 inhibitor - Wikipedia

    en.wikipedia.org/wiki/PDE5_inhibitor

    PDE5 inhibitors have been used as a second line therapy in severe cases of Raynaud phenomenon when it is related to systemic sclerosis per The European Society for Vascular Medicine guidelines. [3] Sildenafil, the prototypical PDE5 inhibitor, was originally discovered during the search of a novel treatment for angina.

  3. Does Adderall Make You Last Longer in Bed or the Opposite? - AOL

    www.aol.com/does-adderall-last-longer-bed...

    If you have dysfunction problems like ED, prescription medication may be a good option to increase stamina. PDE5 inhibitors are ED drugs that can help you get aroused by increasing blood flow to ...

  4. Tadalafil: Your Ultimate Guide to Dosages, Side Effects & More

    www.aol.com/tadalafil-ultimate-guide-dosages...

    This guide to PDE5 inhibitors has more information about how tadalafil, sildenafil and other medications for ED work. There are a number of common use cases for this medication, including:

  5. Tips For Seniors Over 65 With ED - AOL

    www.aol.com/tips-seniors-over-65-ed-125700073.html

    Benign prostatic hyperplasia (BPH). ... PDE5 inhibitors are first-line drugs for treating erectile dysfunction symptoms so you can maintain a full one. ... Other medical treatments for ED at age ...

  6. Phosphodiesterase inhibitor - Wikipedia

    en.wikipedia.org/wiki/Phosphodiesterase_inhibitor

    A phosphodiesterase inhibitor is a drug that blocks one or more of the five subtypes of the enzyme phosphodiesterase (PDE), thereby preventing the inactivation of the intracellular second messengers, cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP) by the respective PDE subtype(s). The ubiquitous presence of this ...

  7. cGMP-specific phosphodiesterase type 5 - Wikipedia

    en.wikipedia.org/wiki/CGMP-specific_phosphodi...

    PDE5 inhibitor drugs are effective in men regardless of why they have erectile dysfunction — including vascular disease, nerve problems, and even psychological causes. [citation needed] PDE5-inhibiting drugs can cause a number of side-effects, including headache, lightheadedness, dizziness, flushing, nasal congestion, and changes in vision.

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