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Extracellular fluid makes up about one-third of body fluid, the remaining two-thirds is intracellular fluid within cells. [3] The main component of the extracellular fluid is the interstitial fluid that surrounds cells.
The intracellular fluid (ICF) is all fluids contained inside the cells, which consists of cytosol and fluid in the cell nucleus. [3] The cytosol is the matrix in which cellular organelles are suspended. The cytosol and organelles together compose the cytoplasm. The cell membranes are the outer barrier.
In anatomy, the interstitium is a contiguous fluid-filled space existing between a structural barrier, such as a cell membrane or the skin, and internal structures, such as organs, including muscles and the circulatory system. [1] [2] The fluid in this space is called interstitial fluid, comprises water and solutes, and drains into the lymph ...
A Darrow Yannet diagram is a schematic used in physiology to identify how the volumes of extracellular fluid and intracellular fluid alter in response to conditions such as adrenal insufficiency and SIADH.
Perilymph is the fluid contained within the bony labyrinth, surrounding and protecting the membranous labyrinth; perilymph resembles extracellular fluid in composition (sodium salts are the predominant positive electrolyte) and, via the cochlear aqueduct (sometimes referred to as the "perilymphatic duct"), is in continuity with cerebrospinal fluid.
The total body of water is divided into fluid compartments, [1] between the intracellular fluid compartment (also called space, or volume) and the extracellular fluid (ECF) compartment (space, volume) in a two-to-one ratio: 28 (28–32) liters are inside cells and 14 (14–15) liters are outside cells.
The membrane enclosing the vesicle is also a lamellar phase, similar to that of the plasma membrane, and intracellular vesicles can fuse with the plasma membrane to release their contents outside the cell. Vesicles can also fuse with other organelles within the cell. A vesicle released from the cell is known as an extracellular vesicle.
Intracellular fluid content in humans. The proportion of cell volume that is cytosol varies: for example while this compartment forms the bulk of cell structure in bacteria, [9] in plant cells the main compartment is the large central vacuole. [10]