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Cushing's syndrome is a collection of signs and symptoms due to prolonged exposure to glucocorticoids such as cortisol. [4] [9] [10] Signs and symptoms may include high blood pressure, abdominal obesity but with thin arms and legs, reddish stretch marks, a round red face due to facial plethora, [11] a fat lump between the shoulders, weak muscles, weak bones, acne, and fragile skin that heals ...
IPSS (inferior petrosal sinus sampling) or BIPSS (bilateral IPSS) is a more accurate but invasive test used to differentiate pituitary from ectopic or adrenal Cushing's syndrome. [15] A corticotropin gradient sample via BIPSS is required to confirm diagnosis when pituitary MRI imaging and biochemical diagnostic tests have been inconclusive. [8]
However, the condition may only be temporary, known as pseudo-Cushing's syndrome (PCS). Therefore, it is important to understand the cause of the syndrome to differentiate between PCS and HCM. [6] HCM itself also has many causes, such as adrenal adenomas and carcinomas causing the adrenal gland to be unresponsive to the negative feedback loop ...
Generally, diseases outlined within the ICD-10 codes E24-E27 within Chapter IV: Endocrine, nutritional and metabolic diseases should be included in this category. The main article for this category is Adrenal gland disorders .
Adrenal gland disorders (or diseases) are conditions that interfere with the normal functioning of the adrenal glands. [1] Your body produces too much or too little of one or more hormones when you have an adrenal gland dysfunction. The type of issue you have and the degree to which it affects your body's hormone levels determine the symptoms. [2]
In order to acquire better treatment strategies, it is important to further examine, study and discern the distinct molecular mechanisms involved in the formation of endogenous Adrenal Adenomas, hyperplasias, and ACTH-independent Cushing's Syndrome to improve the available diagnostic and prognostic markers that can assist clinicians in the ...
ACTH then causes the adrenal glands to release cortisol into the blood. Signs of Cushing's syndrome include muscle weakness, easy bruising, weight gain, male-pattern hair growth , coloured stretch marks, and an excessively reddish complexion in the face. [38] Cushing's syndrome can cause androgen excess and hence the signs and symptoms of ...
Adrenal gland 6. Pancreas 7. Ovary 8. Testes: ... Cushing's disease; Adrenal gland disorders ... List of ICD-9 codes 240-279: Endocrine, nutritional and metabolic ...