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Serious side effects may include low blood pressure, liver problems, psychosis, and QT prolongation. [5] It is unclear if use in pregnancy and breastfeeding is safe. [6] It is an α 2-adrenergic agonist, but how it works is not entirely clear. [5] Tizanidine was approved for medical use in the United States in 1996. [5]
Other common spasmolytic agents include: methocarbamol, carisoprodol, chlorzoxazone, cyclobenzaprine, gabapentin, metaxalone, and orphenadrine. Thiocolchicoside is a muscle relaxant with anti-inflammatory and analgesic effects and an unknown mechanism of action.
Side effects of thiocolchicoside can include nausea, allergy and vasovagal reactions. [15] Liver injury, pancreatitis, seizures, blood cell disorders, severe cutaneous disorders, rhabdomyolysis, and reproductive disorders have all been recorded in the French and European pharmacovigilance databases and in the periodic updates that the companies concerned submit to regulatory agencies.
What is hypertension, and how does high blood pressure lead to health problems? Dr. Leana Wen: Blood pressure is measured in millimeters of mercury or mmHg. It has two readings: Systolic (the top ...
To find out the best breakfast for better blood pressure and heart health, we reached out to Michael Twyman, M.D., a cardiologist at Apollo Cardiology in St. Louis. He stresses the importance of ...
Guidelines on the choice of agents and how best to step up treatment for various subgroups in hypertension (high blood pressure) have changed over time and differ between countries. A Comparison of International Guidelines on Goal Blood Pressure and Initial Therapy for Adults With Hypertension (adapted from JNC 8 guidelines [ 1 ] )
The danger of high blood pressure is that it sneaks up on you, Zidar said. You might not feel bad, but eventually it will wear you down. Think about lowering your blood pressure "like saving a ...
Methocarbamol is a centrally acting skeletal muscle relaxant that has significant potential adverse effects, especially on the central nervous system. [3] Potential side effects of methocarbamol include: Most commonly drowsiness, blurred vision, headache, nausea, and skin rash. [8]