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Other serious side effects may include QT prolongation, heart failure, or bronchospasm. [4] Sotalol is a non-selective β-adrenergic receptor blocker which has both class II and class III antiarrhythmic properties. [1] Sotalol was first described in 1964 and came into medical use in 1974. [5] It is available as a generic medication. [4]
Dofetilide blocks only the rapid K channels; this means that at higher heart rates, when there is increased involvement of the slow K channels, dofetilide has less of an action potential-prolonging effect. Sotalol is indicated for the treatment of atrial or ventricular tachyarrhythmias, and AV re-entrant arrhythmias.
Sotalol. Sotalol has beta-blocking activity. Approximately 2 to 7 percent of patients taking at least 320 mg/day experience proarrhythmia, most often in the form of TdP. [5] The risks and effects are dose-dependent.
Side effects include irregular heartbeat, fatigue, high blood pressure, dry mouth, and eyes that are itchy, red, and/or swollen. Carbonic anhydrase inhibitors (Trusopt, Azopt): This is another ...
A study confirmed that side effects like pancreatitis and kidney damage are possible while taking GLP-1s like Ozempic. Here's what a doctor wants you to know.
Amy Schumer once hopped on board the Ozempic trend, but the side effects were so intense she had to stop.. During a recent appearance on "The Howard Stern Show," the comedian, 43, opened up about ...
Type A: augmented pharmacological effects, which are dose-dependent and predictable [5]; Type A reactions, which constitute approximately 80% of adverse drug reactions, are usually a consequence of the drug's primary pharmacological effect (e.g., bleeding when using the anticoagulant warfarin) or a low therapeutic index of the drug (e.g., nausea from digoxin), and they are therefore predictable.
They also found, however, that GLP-1 drugs were linked to several adverse side effects. Novo Nordisk is the maker of Ozempic, which is approved for type 2 diabetes treatment and reduced risk of ...