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The rhinarium (the leathery part of the nose we see) is quite tough, to allow it to absorb rather rough treatment sometimes. The color varies according to the genotype (genetic makeup) of the cat. A cat's skin has the same color as the fur, but the color of the nose leather is probably dictated by a dedicated gene.
Feline acne is a problem seen in cats primarily involving the formation of blackheads accompanied by inflammation on the cat's chin and surrounding areas that can cause lesions, alopecia, and crusty sores. [1] [2] [3] In many cases, symptoms are mild and the disease does not require treatment. [1]
The coloration of tortoiseshell and calico cats is a visible manifestation of X-inactivation. The black and orange alleles of a fur coloration gene reside on the X chromosome. For any given patch of fur, the inactivation of an X chromosome that carries one allele results in the fur color of the other, active allele.