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At higher doses, side effects (primarily diarrhea, nausea, or vomiting) limit its use. [25] For treating gout symptoms, colchicine is taken orally, with or without food, as symptoms first appear. [26] Subsequent doses may be needed if symptoms worsen. [26]
Signs and symptoms of CDI range from mild diarrhea to severe life-threatening inflammation of the colon. [16]In adults, a clinical prediction rule found the best signs to be significant diarrhea ("new onset of more than three partially formed or watery stools per 24-hour period"), recent antibiotic exposure, abdominal pain, fever (up to 40.5 °C or 105 °F), and a distinctive foul odor to the ...
While many different things can cause diarrhea—including infections or a more serious gastrointestinal condition—in most cases, it will go away after a few days without the need for treatment.
Colomycin has a recommended intravenous dose of 1 to 2 million units three times daily for patients weighing 60 kg or more with normal renal function. Coly-Mycin has a recommended dose of 2.5 to 5 mg/kg colistin base a day, which is equivalent to 6 to 12 mg/kg colistimethate sodium per day.
This can also help develop new treatment strategies by researchers for more effective treatments. [9] By enriching the knowledge of commonly prescribed drugs, pharmacy students will be more familiar with their mechanism of action, first-line therapy indications and side effects.
While colchicine is not used to treat cancer in humans, it is commonly used to treat acute attacks of gout. [26] Colchicine is an anti-inflammatory drug that has been in continuous use for more than 3000 years. Colchicine is an oral drug, known to be used for treating acute gout and preventing acute attacks of familial Mediterranean fever (FMF).
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