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A pyogenic granuloma or lobular capillary hemangioma [3] is a vascular tumor that occurs on both mucosa and skin, and appears as an overgrowth of tissue due to irritation, physical trauma, or hormonal factors. [4] [5] It is often found to involve the gums, skin, or nasal septum, and has also been found far from the head, such as in the thigh. [6]
Granulation tissue is new connective tissue and microscopic blood vessels that form on the surfaces of a wound during the healing process. [1] Granulation tissue typically grows from the base of a wound and is able to fill wounds of almost any size. Examples of granulation tissue can be seen in pyogenic granulomas and pulp polyps.
The skin weighs an average of four kilograms, covers an area of two square metres, and is made of three distinct layers: the epidermis, dermis, and subcutaneous tissue. [1] The two main types of human skin are: glabrous skin, the hairless skin on the palms and soles (also referred to as the "palmoplantar" surfaces), and hair-bearing skin. [3]
The recurrence rate for EDC is considered by many (National Comprehensive Cancer Network) to be too high for use on many facial regions, and on recurrent skin cancer. [6] [7] As a surgical ulcer is created and is larger than the original tumor, healing time may be delayed and subsequent scarring obvious. [citation needed]
When surgical removal of the granuloma is not applicable due to size or location, the lesions have been found to respond well to radiation therapy as well as glucocorticoids or steroids. [3] While recurrence rate for plasma cell granulomas is very low, they have been reported; therefore, it is recommended that patients come back for yearly ...
This type of epulis is neither pyogenic ("pus producing") nor a true granuloma, but it is a vascular lesion.About 75% of all pyogenic granulomas occur on the gingiva, [2] growing beneath the gingival margin, [8] although they may also occur elsewhere in the mouth or other parts of the body (where the term epulis is inappropriate).
Instead, the three are associated with each other because they appear frequently on gingiva: pyogenic granuloma and peripheral giant cell granuloma. Some researchers believe peripheral ossifying fibromas to be related to pyogenic fibromas and, in some instances, are the result of a pyogenic granuloma which has undergone fibrosis and calcification.
English: Histopathology of pyogenic granuloma - high magnification. HE stain. Annotated are major features: Endothelial cell clusters, inflammation, variable amount of mitoses, and edema. - Christopher S. Hale, M.D.. Skin nonmelanocytic tumor - Vascular tumors - Capillary / pyogenic granuloma. PathologyOultines. Topic Completed: 1 August 2012.