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Sideroblastic anemia, or sideroachrestic anemia, is a form of anemia in which the bone marrow produces ringed sideroblasts rather than healthy red blood cells (erythrocytes). [1] In sideroblastic anemia, the body has iron available but cannot incorporate it into hemoglobin , which red blood cells need in order to transport oxygen efficiently.
Basophilic stippling, also known as punctate basophilia, is the presence of numerous basophilic granules that are dispersed through the cytoplasm of erythrocytes in a peripheral blood smear. They can be demonstrated to be RNA .
Pappenheimer bodies are abnormal basophilic granules of iron found inside red blood cells on routine blood stain. [1] They are a type of inclusion body composed of ferritin aggregates, or mitochondria or phagosomes containing aggregated ferritin. They appear as dense, blue-purple granules within the red blood cell and there are usually only one ...
Ringed sideroblasts (10 or more iron granules encircling one-third or more of the nucleus) seen on Perls' Prussian blue iron stain (>15% ringed sideroblasts when counted among red cell precursors for refractory anemia with ring sideroblasts) Megakaryocytic series (can be the most subjective) [citation needed]:
Basophilic is a technical term used by pathologists. It describes the appearance of cells , tissues and cellular structures as seen through the microscope after a histological section has been stained with a basic dye .
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One drink is defined as 1.5 ounces of liquor, 12 ounces of beer or 5 ounces of wine. Taub-Dix points out that alcoholic cocktails are often made with ingredients like mixers, syrups and juice drinks.
Coarse basophilic stippling occurs in other cases as seen in Table 1. [10] As IDA and ACD can often be confused, it is important to evaluate their laboratory parameters. IDA is associated with low hemoglobin, ferritin, transferrin saturation, and MCV. [4] It is also associated with a normal C-reactive protein and high transferrin. [4]