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Lipoprotein(a) (LPA) is a lipoprotein particle of a certain phenotype; High-density lipoproteins (HDL) collect fat molecules from the body's cells/tissues and take them back to the liver. HDLs are sometimes referred to as "good" lipoprotein because higher concentrations correlate with low rates of atherosclerosis progression and/or regression.
Low-density lipoprotein receptor-related protein 5 is a protein that in humans is encoded by the LRP5 gene. [ 5 ] [ 6 ] [ 7 ] LRP5 is a key component of the LRP5/ LRP6 / Frizzled co-receptor group that is involved in canonical Wnt pathway .
LRP6 is a transmembrane low-density lipoprotein receptor that shares a similar structure with LRP5. In each protein, about 85% of its 1600-amino-acid length is extracellular. Each has four YWTD β-propeller motifs at the amino terminal end that alternate with four epidermal growth factor (EGF)-like repeats, followed by three LDLR type A repeats ...
High-density lipoprotein (HDL) is one of the five major groups of lipoproteins. [1] Lipoproteins are complex particles composed of multiple proteins which transport all fat molecules around the body within the water outside cells. They are typically composed of 80–100 proteins per particle (organized by one, two or three ApoA). HDL particles ...
Another hormone that may affect lipogenesis through the SREBP-1 pathway is leptin. It is involved in the process by limiting fat storage through inhibition of glucose intake and interfering with other adipose metabolic pathways. [1] The inhibition of lipogenesis occurs through the down regulation of fatty acid and triglyceride gene expression. [10]
4018 n/a Ensembl ENSG00000198670 n/a UniProt P08519 n/a RefSeq (mRNA) NM_005577 n/a RefSeq (protein) n/a n/a Location (UCSC) Chr 6: 160.53 – 160.66 Mb n/a PubMed search n/a Wikidata View/Edit Human Lipoprotein(a) is a low-density lipoprotein variant containing a protein called apolipoprotein(a). Genetic and epidemiological studies have identified lipoprotein(a) as a risk factor for ...
Low density lipoprotein receptor-related protein 1 (LRP1), also known as alpha-2-macroglobulin receptor (A2MR), apolipoprotein E receptor (APOER) or cluster of differentiation 91 (CD91), is a protein forming a receptor found in the plasma membrane of cells involved in receptor-mediated endocytosis. In humans, the LRP1 protein is encoded by the ...
Low-density lipoprotein (LDL) is one of the five major groups of lipoprotein that transport all fat molecules around the body in extracellular water. [1] These groups, from least dense to most dense, are chylomicrons (aka ULDL by the overall density naming convention), very low-density lipoprotein (VLDL), intermediate-density lipoprotein (IDL ...