Search results
Results From The WOW.Com Content Network
It remains unclear why Baeyer chose to name the compound that he discovered "barbituric acid". In his textbook Organic Chemistry, the American organic chemist Louis Frederick Fieser (1899–1977) initially speculated that the name stemmed from the German word Schlüsselbart (literally, the beard (Bart, Latin: barba) of a key (Schlüssel), that is, the bit of a key), because Baeyer had regarded ...
Barbital (or barbitone), sold under the brand names Veronal for the pure acid and Medinal for the sodium salt, was the first commercially available barbiturate. It was used as a sleeping aid from 1903 until the mid-1950s. The chemical names for barbital are diethylmalonyl urea or diethylbarbituric acid; hence, the sodium salt is known also as ...
Pliny the Elder, who lived from 23–79 CE, first gave a name to what we now call pills, calling them pilula. [2] Pliny also wrote Naturalis Historia a collection of 38 books and the first pharmacopoea. Pedanius Dioscorides wrote De Materia Medica (c. 40 – 90 CE); this book dominated the area of drug knowledge for some 1500 years until the ...
Barbituric acid, the parent structure of all barbiturates. Barbiturates [a] are a class of depressant drugs that are chemically derived from barbituric acid. [2] They are effective when used medically as anxiolytics, hypnotics, and anticonvulsants, but have physical and psychological addiction potential as well as overdose potential among other possible adverse effects.
Alphenal, also known as 5-allyl-5-phenylbarbituric acid, is a barbiturate derivative developed in the 1920s. [1] It has primarily anticonvulsant properties and was used occasionally for the treatment of epilepsy or convulsions, although not as commonly as better known barbiturates such as phenobarbital.
His research group synthesised the first free dipeptide (Glycine-Glycine) in 1901. [12] By 1906 about 65 peptides of different chain length and amino acid composition had been made by his research group. His researches made from 1899 to 1906 were published in 1907 with the title Untersuchungen über Aminosauren, Polypeptides und Proteine. [13]
Brallobarbital was a barbiturate developed in the 1920s. [1] It has sedative and hypnotic properties, and was used for the treatment of insomnia.Brallobarbital was primarily sold as part of a combination product called Vesparax, composed of 150 mg secobarbital, 50 mg brallobarbital and 50 mg hydroxyzine. [2]
Tuinal was the brand name of a discontinued combination drug composed of two barbiturate sodium salts (secobarbital and amobarbital) in equal proportions. Tuinal was introduced as a sedative-hypnotic (sleeping pill) medication in the late 1940s by Eli Lilly. It was also used in obstetrics for childbirth.